SCP-ZH-310

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  Title: Anomalous Protein Domain
  Author: SamScript
  Translator: vomiter

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Picture of unactivated zh310-AP-4 protein. The red circle indicates SCP-ZH-310 domain. The top in the picture is a binding site for nano particles of beryllium bronze.

Item #: SCP-ZH-310

Object Class: Euclid

Special Containment Procedures: Due to the nature of SCP-ZH-310 in molecular biology, it is impossible and unnecessary to prevent or contain its existence in an extra extent. Departments concerned should spend containment resources supervising research studies on in vitro stable misfolded protein structures, non functional genes and epigenetics along with monitoring if there are academic articles with technical terms related to anomalous abilities, such as "reality bending", "ontokinetic" and "biological Einstein-Rosen Bridge¹" in order to prevent civilian from discovering the anomalous effects of SCP-ZH-310 derived proteins.

If a concerned research study starts, Class C amnestics are to be administered to the research team, and memetic agents are to be implanted into the related realm, in order to preserve the normalcy in public cognition.

Biochemical examinations conducted by the Foundation to anomalous humanoids are to be expanded with assessments related to SCP-ZH-310, including but not limited to species of SCP-ZH-310 derived proteins, unit density, activity of specimens, RSCR². Information with more details has been announced on the website of the Medical Association of the Foundation, allowed for researchers in concerned fields with class 2 clearance or above to access.

Site facilities related with anomalous humanoids in the Foundation English branch (such as Site-17, Site-66, Site-88) should send a biochemistry report about of currently-contained anomalous humanoids to Site-ZH-44, the Foundation Biomedical Association and Biochemical Society of the Foundation for research study reference.

Zh310-AP-4b-ar, a new-type mnestic developed by Site-ZH-44 collaborated with Antimemetics Division, is allowed to be applied under [REDACTED].
It is unsupported to reinforce and improve the expression of SCP-ZH-310 in any humanoids, and so is drug study.

Description: SCP-ZH-310 is a protein domain, with which a series of proteins can perform anomalous properties. It is found in a cross comparison between cranial nerves of regular humans and those of 45 anomalous entities. There have been eight members found in this family. To see them all, check the list of SCP-ZH-310 derivatives.

Expression of SCP-ZH-310 is regulated with several established biochemical mechanisms in human, and therefore it is rare to form an actual anomaly. The genes corresponding to SCP-ZH-310 is usually viewed as non-coding locus³ under circumstances consistent with modern models in biology, and with common epigenetic⁴ practices⁵, 94% of its transcription⁶ has been repressed, making it nearly impossible to express in a regular person.

Even if SCP-ZH-310 manages to go through translation⁷ and folding⁸ modification where the tertiary structures⁹ are formed, there are still up to 99.2% chance of being degraded¹⁰ as a misfolded protein in proteasome¹¹. Only 0.8% population of people has their body not treat it as a misfolded one and retain the domain, leading it to become an anomalous protein.

As the intensity of SCP-ZH-310 expression is limited on the large scale, only 45% among those individuals who can steadily express SCP-ZH-310 would eventually transform themselves into anomalous entities.

Retrospective studies have proved that ███ instances of objects contained by the Foundation is capable of steadily expressing SCP-ZH-310 and its derivatives. Such instances account for 74% of humanoid anomalous entities currently in the Foundation containment.

List of SCP-ZH-310 derivatives

Item	Location	Affect	Remark
zh310-AP-1	Distributed mainly in ██ and ██ areas of prefrontal cortex, sporadically sacrum, thymus and sacral ganglia	Large accumulation of the protein can lead the hume reading in a human body to increase, and meanwhile decrease hume reading of the human body surround, resulting in reality instability	It can be detected in each known specimens of reality bending entities that is available for assessment.
zh310-AP-1b	Distributed sporadically in ██ and ██ areas of prefrontal cortex, mainly sacrum, thymus and sacral ganglia	310-AP-1 and it are the antagonist of each other. It can balance the hume readings of human body and that of surroundings into the same level. (error < 30 centihume)	Given that it possesses the property similar to reality anchors, check addendum ZH-310-1 for further information.
zh310-AP-2	Distributed in ██, ██, ██, ██ areas of prefrontal cortex.	It may release certain electro signals and connect to other organisms around, leading to partially control on the organisms' brain neuro transduction.	A proposal to reclassify it into another SCP object with Keter class has been submitted. Check addendum ZH-310-2 for further information.
zh310-AP-3	Distributed sporadically in extremity nerve ending synapses and motor end plate, and ██ area in the brain.	In vitro12 indicates it carries the effect of making time-space distortion and changing gravity fields. There are no human instance performs obvious outer effects so far.	Highly consistent with lipoprotein of SCP-4850 instances. Further researches have been requested.
zh310-AP-4	Distributed sporadically in █ area of the parietal lobe, ██ area of the occipital lobe and the hippocampus.; largely accumulated in SCP-073's brain.	The core of the domain can carry a nano beryllium bronze molecule. It can induce resistance against various cognitohazard, memetic hazard, antimemetic hazard, and it increases long-term memory ability by 53%.	The Foundation [REDACTED] Division has requested a collaboration research project to develop Class C mnestic, pending approval from Site-ZH-44 Site Director, [REDACTED].
zh310-AP-4b	[DATA EXPUNGED]	[DATA EXPUNGED]	[DATA EXPUNGED]
zh310-AP-5	Distributed in blood vessel epithelial cells and connective tissues, or homogeneously generalized distribution if it can be produced into the adequate amount.	It can improve the chimerism between organic material and metal particles, and promotes release of an unknown cytokine, reducing immune rejection.	Research on its expression in anomalous entities belonging to WAN sect.
zh310-AP-6	Largely existing in epithelial cells and cortical α and β cell of SCP-3480's abdominal radio emitting organ13.	The frequency emitted by the organ can significantly increase the expression and survival of SCP-ZH-310 in cells. (p=0.03)

Addendum

Addendum-ZH-310-1: Proposal for Protocol NINHURSAG

Given that the SCP-ZH-310 derivative, zh310-AP-1b possesses potential reality stabilizing capability, the former responsible person, Dr. Zymosan submitted a request for project fund to the main branch of the Foundation on █/█/████ along with research team of Site-ZH-44, in order to understand and intensify zh310-AP-1b expression, minimizing cognition posed by reality bending on people. The proposal was eventually rejected.

Check Proposal Content

Protocol NINHURSAG

If the Foundation, in biomedical field, finds an object may benefit containment of anomaly or consolidate normalcy, the research on it can be promoted, and the results of intensification or inverse operation can be implanted into humanity, in order to raise the overall stability and the chance of survival of human civilization.

Related Documents Excerpts

From： Dr. Zymosan, Site-ZH-44
To： The Foundation Biomedical Association (SCPFBMA)

….Given that zh310-AP-1h, one of SCP-ZH-310 derivatives, possesses potential to be a natural SRA¹⁴, along with the fact that the object has been known to generally exist in ordinary human body, our research division proposes to reactivate Protocol NINHURSAG in Site-ZH-44. Hopefully raise the resistance against reality bending anomalies for the Foundation and humanity after this object being fully studied.

— former responsible person for SCP-ZH-310 project, Dr. Zymosan

From： VerStradt, SCPFBMA
To： Dr. Zymosan, Site-ZH-44

Proposal refused. The Foundation's purpose is to maintain "normalcy". A reality stabilizing protein having existed in our body is considered normalcy; strengthening our cognition toward normalcy with anomalies is still anomalous. We had employed too much anomaly to maintain the "normalcy" determined by humanity; from the ethic committee's point of view, these procedures tend to end up shooting ourselves in the foot, compromising our motto in a grey zone. We certainly do not need to worsen it ourselves.

The fund that your team proposed has no problem. It is quite interesting to find out why humans carry a protein with reality stabilizing mechanism. However, intensification of human's proper reality stabilizing capacity is actually creating another group of Type Green. This is not containment but the reverse. Therefore, the protocol will not be enforced for the object in question.

Besides, Site-ZH-44 Site Director, you need to improve your application checking process and personnel education. Do not forget the meaning of our motto and the veil protocol. From now on, you should talk to your on-site researching personnel before they submit any unrestrained proposal, in case it would be seemingly impetuous.


— Vers Stratedson, The Foundation Biomedical committee and ethic committee.

Addendum-ZH-310-2: Project Moonset

In the test on NASHAE¹⁵, the Foundation found SCP-1000 instances carrying zh310-AP-2 of a level significantly higher than Homo sapiens and other samples. (p=0.015)

██/██/████, Dr. Flavir and three researchers from Site-ZH-44 was invited into Project Moonset.

[3/1000 Clearance Required]

Project Moonset

Leading by the responsible team for SCP-1000, the teams from Site-ZH-44, Site-66 SCPFBMA are to collaborate to find out the sources from which the SCP-1000 ancient civilization developed organism manipulating techniques.

Research Process

[2/Project Moonset Clearance Required]

[5/ZH-310 Clearance Required]
[4/1000 Clearance or Above Required]

Research Result Excerpt

• SCP-ZH-310 is actually an artificial protein domain, the product of SCP-1000 civilization technology.
• zh310-AP-2 is a natural protein in SCP-1000, from which SCP-1000 reversely extract SCP-ZH-310, and developed other SCP-ZH-310 derivatives.
• Due to the Dominance of SCP-1000 towards humanity in the past, Homo sapiens were often employed as experiment subjects in the history of SCP-ZH-310 researching, leading its hereditary factors to enter gene pool of Homo sapiens.
• zh310-AP-2 is the major channel through which SCP-1000 manipulate other living objects or organisms. With a large amount of the protein expression, they managed to construct non-contact neural connection with other creatures, and therefore manipulate other species and organisms, creating a "Children of the Night civilization" different from that of Homo sapiens.
• In human bodies exist multiple breaking mechanisms towards SCP-ZH-310, resulted from SCP-1000 employing virus agents to spread and regulate biochemical pathways in humans to prevent an SK class Dominance Shift Scenario.
• It is speculated that SCP-1000 contaminated part of SCP-1000 population with the same virus agents employed in the above-mentioned regulation process, resulted in a part of SCP-1000 losing their non-contact neural connecting ability, which directly or indirectly weakened its civilization.
• zh310-AP-2 expression negatively correlates with carbon dioxide concentration in the atmosphere (R²=0.89), which means that climate changes and current environmental pollution suppressed the non-contact neural connecting ability of SCP-1000.

Given the special property of zh310-AP-2, a proposal to classify the protein as a new SCP object has been submitted, now pending the deliberation Site-ZH Headquarter, SCPFBMA and O5 council.

Addendum-ZH-310-3：[DATA EXPUNGED]

[4/ZH-310 Clearance Required]

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[DATA EXPUNGED]

Incident Recording

Incident ZH-310-1:

6/3/2019, in Site-ZH-44 occurred a security event, where D-243726 neutralized memetic kill agents in the facility. After the security personnel's arrival, D-243726 was accidentally terminated with shots. Autopsy reports revealed that there was a great amount of beryllium bronze found within the interior of blood vessels and the brain. Further study confirmed that it was a homologue of zh310-AP-4b, a SCP-ZH-310 derivative, consistent with the mnestic developed by the Division of [REDACTED] collaborated with Site-ZH-44.

After the incident, Dr. Surge, the Site Director conducted an interview with Dr. Zymosan, the responsible person for SCP-ZH-310 when the incident occurred.

[4/ZH-310 Clearance Required]

Time: 6/4/2019 20:49
Interviewer: Site-ZH-44 Director, Dr. Surge
Interviewed Dr. Zymosan

Dr. Surge： So, how did that D-class manage to escape?

Dr. Zymosan： 4b-ar is out of control. We thought it works, but it works too much. It not only consolidate memories as mnestics, not only help to resist amnestic, info-hazard, memetic kill agents …. It's not only the antagonist¹⁶ of AP-4, I think it also has properties of AP-2, just of a more violent version.

Dr. Surge： And you used it on a D-class —

Dr. Zymosan： He's out of control and far more beyond our prediction. We've succeeded but we've also failed.

Dr. Surge：（Take two deep breaths）Fine.

Dr. Zymosan： Sam, 4b must be deleted. The whole project must be deleted. Things Wheeler wants us to do is ruined. You know what their division do. The whole project must be deleted, with nothing left. (Pause) And frankly speaking, I don't think this should be left. Just imagine what if GoI or someone else gets this ….

Dr. Surge： I know. I know.

(Silence lasted for fifteen seconds)

Dr. Surge： So, what are you going to do? I wish I could say it's not your fault. But you know the rules.

Dr. Zymosan： I know. The Foundation don't do it this way. I've familiar with their rules. That means no rules.

Dr. Zymosan： I've fed up with being at fucking mercy of the Foundation. NINHURSAG is also what they've made up. 3031 is suitable, but there's no chance for us. We're just a small site, can do nothing but being a puppet for the superiors. BMA, Ethic Committee, Amemetic Division¹⁷. We just follow the procedures and loses every time.

Dr. Surge： I know how you feel, but still be careful about what to say. You know where these'll end up.

Dr. Zymosan： Don't be worried. Anyway, I've planned the next step when that incident happened.

Dr. Surge： What do you mean?

Dr. Zymosan： I quit.

[End of the Interview]

Dr. Zymosan resigned two weeks after the interview, received standard amnestic procedures for resigning personnel of the Foundation. The responsible person for the object is currently Dr. Flavir.

Incident ZH-310-2:

In inventory on █/█/2019, zh-310-4b sample was found missing. Site security camera provided no further clue. The Foundation is tracking Dr. Zymosan's whereabouts. The search is ongoing.

Footnotes

1. ERB, or a wormhole

2. Reality Stability-Concentration Rate. The unit is Humes/μL.

3. Non-coding genes are the genes that do not carry protein message. They are usually involved in formation of RNA regulatory factors. Non-coding genes composed an overwhelming part of human genome.

4. Epigenetics exclusively focuses on the biochemical mechanisms through which gene expression is regulated without changing the message carried by the heditrary materials (usually DNA). To make it easy to understand, it means to lock up the gene without editing it, directly blocking the gene from expression.

5. Phenomona that have been observed include histone clamp and CpG islands of SCP-ZH-310 relating genes being methylated. "General Biomedics Regarding the Foundation Containing Organisms (22th ed. )"; Dr. J.R.Yu et. al.; The Foundation Biomedical Association.

6. Transcription, according to central dogma of molecular biology, means the process through which DNA molecular message is copied into an RNA molecule.

7. Translate, according to central dogma of molecular biology, means the process through which the message on an RNA molecule is decoded and a peptide chain is formed.

8. Folding is the process through which a peptide chain is twisted into an active form. Only the proteins that are folded correctly can exect biological function, and the misfolded ones are often degraded.

9. The spatial structure of a protein

10. Degrade means the process through which a protein is broken down into amino acids.

11. Proteasome is a protein in a barrel-like shape. It degrades other proteins.

12. A term in biological research. In vitro means the studied cell or tissue is put at outside of a living body environment. The contrast is in vivo, which means in living body environment.

13. In the abdominal organ of SCP-3480, α cells compose the radio emitting tissue, and β cells compose the receiving one. The neural signal correlates with [REDACTED] area in the brain. "Research Report Regarding SCP-3480's physiological anomalies ( 4th ed. )"; Dr. Dietz et. al.; The Foundation Head Academic Association; 20██

14. Scranton Reality Anchor, for further information please check "Introduction to Reality Baseline and Ontokinetic(9th ed. )"; Dr. R. Scranton; The Foundation Head Academic Association; 19██

15. Not Homo Sapiens Humanoid Anamolous Entity.

16. Scranton Reality Anchor, for further information please check "Introduction to Reality Baseline and Ontokinetic(9th ed. )"; Dr. R. Scranton; The Foundation Head Academic Association; 19██

17. You left out this not deleted, Surge you'd better use your fucking clearance to recompile this article. I'm not going to clean up the mess you people made again. — Flavir